MeCP2 represses the rate of transcriptional initiation of highly methylated long genes

Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to understand how MeCP2 regulates transcription because MeCP2 binds broadly across the genome, and MeCP2 mutations are associated with widespread small...

全面介紹

Na minha lista:
書目詳細資料
發表在:Mol Cell
Main Authors: Boxer, Lisa D., Renthal, William, Greben, Alexander W., Whitwam, Tess, Silberfeld, Andrew, Stroud, Hume, Li, Emmy, Yang, Marty G., Kinde, Benyam, Griffith, Eric C., Bonev, Boyan, Greenberg, Michael E.
格式: Artigo
語言:Inglês
出版: 2019
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982532/
https://ncbi.nlm.nih.gov/pubmed/31784358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.032
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍