MeCP2 represses the rate of transcriptional initiation of highly methylated long genes

Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to understand how MeCP2 regulates transcription because MeCP2 binds broadly across the genome, and MeCP2 mutations are associated with widespread small...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Boxer, Lisa D., Renthal, William, Greben, Alexander W., Whitwam, Tess, Silberfeld, Andrew, Stroud, Hume, Li, Emmy, Yang, Marty G., Kinde, Benyam, Griffith, Eric C., Bonev, Boyan, Greenberg, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982532/
https://ncbi.nlm.nih.gov/pubmed/31784358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.032
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados