Cargando...

DNA methylation in the gene body influences MeCP2-mediated gene repression

Rett syndrome is a severe neurodevelopmental disorder caused by mutations in the methyl-CpG binding protein gene (MECP2). MeCP2 is a methyl-cytosine binding protein that is proposed to function as a transcriptional repressor. However, multiple gene expression studies comparing wild-type and MeCP2-de...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kinde, Benyam, Wu, Dennis Y., Greenberg, Michael E., Gabel, Harrison W.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206576/
https://ncbi.nlm.nih.gov/pubmed/27965390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618737114
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!