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DNA methylation in the gene body influences MeCP2-mediated gene repression
Rett syndrome is a severe neurodevelopmental disorder caused by mutations in the methyl-CpG binding protein gene (MECP2). MeCP2 is a methyl-cytosine binding protein that is proposed to function as a transcriptional repressor. However, multiple gene expression studies comparing wild-type and MeCP2-de...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206576/ https://ncbi.nlm.nih.gov/pubmed/27965390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618737114 |
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