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Disruption of DNA methylation-dependent long gene repression in Rett syndrome
Disruption of the MECP2 gene leads to Rett syndrome (RTT), a severe neurological disorder with features of autism(1). MECP2 encodes a methyl-DNA-binding protein(2) that has been proposed to function as a transcriptional repressor, but despite numerous studies examining neuronal gene expression in Me...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480648/ https://ncbi.nlm.nih.gov/pubmed/25762136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14319 |
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