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CITCO Directly Binds to and Activates Human Pregnane X Receptor

The xenobiotic receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are activated by structurally diverse chemicals to regulate the expression of target genes, and they have overlapping regulation in terms of ligands and target genes. Receptor-selective agonists are, theref...

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Опубликовано в: :Mol Pharmacol
Главные авторы: Lin, Wenwei, Bwayi, Monicah, Wu, Jing, Li, Yongtao, Chai, Sergio C., Huber, Andrew D., Chen, Taosheng
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978709/
https://ncbi.nlm.nih.gov/pubmed/31882411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.118513
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