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CITCO Directly Binds to and Activates Human Pregnane X Receptor

The xenobiotic receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are activated by structurally diverse chemicals to regulate the expression of target genes, and they have overlapping regulation in terms of ligands and target genes. Receptor-selective agonists are, theref...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Lin, Wenwei, Bwayi, Monicah, Wu, Jing, Li, Yongtao, Chai, Sergio C., Huber, Andrew D., Chen, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978709/
https://ncbi.nlm.nih.gov/pubmed/31882411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.118513
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