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CITCO Directly Binds to and Activates Human Pregnane X Receptor
The xenobiotic receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are activated by structurally diverse chemicals to regulate the expression of target genes, and they have overlapping regulation in terms of ligands and target genes. Receptor-selective agonists are, theref...
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| Veröffentlicht in: | Mol Pharmacol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978709/ https://ncbi.nlm.nih.gov/pubmed/31882411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.118513 |
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