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The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY

LacY catalyzes accumulation of galactosides against a concentration gradient by coupling galactoside and H(+) transport (i.e., symport). While alternating access of sugar- and H(+)-binding sites to either side of the membrane is driven by binding and dissociation of sugar, the electrochemical H(+) g...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jiang, Xiaoxu, Ermolova, Natalia, Lim, John, Choi, Seo Woo, Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969543/
https://ncbi.nlm.nih.gov/pubmed/31889006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916563117
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