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An Asymmetric Conformational Change in LacY

Galactoside/H(+) symport by the lactose permease of Escherichia coli (LacY) involves reciprocal opening and closing of periplasmic and cytoplasmic cavities so that sugar- and H(+)-binding sites become alternatively accessible to either side of the membrane. After reconstitution into proteoliposomes,...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Smirnova, Irina, Kasho, Vladimir, Jiang, Xiaoxu, Kaback, H. Ronald
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456262/
https://ncbi.nlm.nih.gov/pubmed/28300394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00134
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