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Towards a mechanistic understanding of DNA methylation readout by transcription factors
Epigenetic DNA modification impacts gene expression, but the underlying molecular mechanisms are only partly understood. Adding a methyl group to a cytosine base locally modifies the structural features of DNA in multiple ways, which may change the interaction with DNA-binding transcription factors...
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| Pubblicato in: | J Mol Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961349/ https://ncbi.nlm.nih.gov/pubmed/31689433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.10.021 |
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