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A unified approach for quantifying and interpreting DNA shape readout by transcription factors

Transcription factors (TFs) interpret DNA sequence by probing the chemical and structural properties of the nucleotide polymer. DNA shape is thought to enable a parsimonious representation of dependencies between nucleotide positions. Here, we propose a unified mathematical representation of the DNA...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Rube, H Tomas, Rastogi, Chaitanya, Kribelbauer, Judith F, Bussemaker, Harmen J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822049/
https://ncbi.nlm.nih.gov/pubmed/29472273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177902
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