A unified approach for quantifying and interpreting DNA shape readout by transcription factors

Transcription factors (TFs) interpret DNA sequence by probing the chemical and structural properties of the nucleotide polymer. DNA shape is thought to enable a parsimonious representation of dependencies between nucleotide positions. Here, we propose a unified mathematical representation of the DNA...

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Vydáno v:Mol Syst Biol
Hlavní autoři: Rube, H Tomas, Rastogi, Chaitanya, Kribelbauer, Judith F, Bussemaker, Harmen J
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Methods
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822049/
https://ncbi.nlm.nih.gov/pubmed/29472273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177902
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