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Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein–DNA binding
BACKGROUND: DNA shape analysis has demonstrated the potential to reveal structure-based mechanisms of protein–DNA binding. However, information about the influence of chemical modification of DNA is limited. Cytosine methylation, the most frequent modification, represents the addition of a methyl gr...
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| Pubblicato in: | Epigenetics Chromatin |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800008/ https://ncbi.nlm.nih.gov/pubmed/29409522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0174-4 |
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