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Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding
Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still not completely understood how proteins recognize their target sites in the genome. Besides hydrogen bonding in the major groove (base readout), proteins recognize minor-groove geometry using positively charg...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716191/ https://ncbi.nlm.nih.gov/pubmed/29040720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx915 |
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