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Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding

Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still not completely understood how proteins recognize their target sites in the genome. Besides hydrogen bonding in the major groove (base readout), proteins recognize minor-groove geometry using positively charg...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Chiu, Tsu-Pei, Rao, Satyanarayan, Mann, Richard S., Honig, Barry, Rohs, Remo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716191/
https://ncbi.nlm.nih.gov/pubmed/29040720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx915
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