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Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding

Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still not completely understood how proteins recognize their target sites in the genome. Besides hydrogen bonding in the major groove (base readout), proteins recognize minor-groove geometry using positively charg...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Chiu, Tsu-Pei, Rao, Satyanarayan, Mann, Richard S., Honig, Barry, Rohs, Remo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716191/
https://ncbi.nlm.nih.gov/pubmed/29040720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx915
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