Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding

Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still not completely understood how proteins recognize their target sites in the genome. Besides hydrogen bonding in the major groove (base readout), proteins recognize minor-groove geometry using positively charg...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Chiu, Tsu-Pei, Rao, Satyanarayan, Mann, Richard S., Honig, Barry, Rohs, Remo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716191/
https://ncbi.nlm.nih.gov/pubmed/29040720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx915
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge