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Deconvolving the recognition of DNA shape from sequence

Protein-DNA binding is mediated by the recognition of the chemical signatures of the DNA bases and the three-dimensional shape of the DNA molecule. Because DNA shape is a consequence of sequence, it is difficult to dissociate these modes of recognition. Here, we tease them apart in the context of Ho...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Abe, Namiko, Dror, Iris, Yang, Lin, Slattery, Matthew, Zhou, Tianyin, Bussemaker, Harmen J, Rohs, Remo, Mann, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422406/
https://ncbi.nlm.nih.gov/pubmed/25843630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.008
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