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Covariation between homeodomain transcription factors and the shape of their DNA binding sites

Protein–DNA recognition is a critical component of gene regulatory processes but the underlying molecular mechanisms are not yet completely understood. Whereas the DNA binding preferences of transcription factors (TFs) are commonly described using nucleotide sequences, the 3D DNA structure is recogn...

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Detalhes bibliográficos
Main Authors: Dror, Iris, Zhou, Tianyin, Mandel-Gutfreund, Yael, Rohs, Remo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874178/
https://ncbi.nlm.nih.gov/pubmed/24078250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt862
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