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How motif environment influences transcription factor search dynamics: Finding a needle in a haystack
Transcription factors (TFs) have to find their binding sites, which are distributed throughout the genome. Facilitated diffusion is currently the most widely accepted model for this search process. Based on this model the TF alternates between one‐dimensional sliding along the DNA, and three‐dimensi...
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| Publicado no: | Bioessays |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023137/ https://ncbi.nlm.nih.gov/pubmed/27192961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600005 |
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