SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

The DNA-binding interfaces of the androgen (AR) and glucocorticoid (GR) receptors are virtually identical, yet these transcription factors share only about a third of their genomic binding sites and regulate similarly distinct sets of target genes. To address this paradox, we determined the intrinsi...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Zhang, Liyang, Martini, Gabriella D., Rube, H. Tomas, Kribelbauer, Judith F., Rastogi, Chaitanya, FitzPatrick, Vincent D., Houtman, Jon C., Bussemaker, Harmen J., Pufall, Miles A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749176/
https://ncbi.nlm.nih.gov/pubmed/29196557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.222844.117
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