Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes

Although DNA modifications play an important role in gene regulation, the underlying mechanisms remain elusive. We developed EpiSELEX-seq to probe the sensitivity of transcription factor binding to DNA modification in vitro using massively parallel sequencing. Feature-based modeling quantifies the e...

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Udgivet i:Cell Rep
Main Authors: Kribelbauer, Judith F., Laptenko, Oleg, Chen, Siying, Martini, Gabriella D., Freed-Pastor, William A., Prives, Carol, Mann, Richard S., Bussemaker, Harmen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533174/
https://ncbi.nlm.nih.gov/pubmed/28614722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.069
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