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Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes. Remodeling of the pancreatic stroma occurs during PDAC development, which drives disease progressio...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Vennin, Claire, Rath, Nicola, Pajic, Marina, Olson, Michael F., Timpson, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959285/
https://ncbi.nlm.nih.gov/pubmed/28972449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1345712
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