Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes. Remodeling of the pancreatic stroma occurs during PDAC development, which drives disease progressio...

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Vydáno v:Small GTPases
Hlavní autoři: Vennin, Claire, Rath, Nicola, Pajic, Marina, Olson, Michael F., Timpson, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Mini-Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959285/
https://ncbi.nlm.nih.gov/pubmed/28972449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1345712
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