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Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

Our recent publication demonstrates that transient inhibition of Rho-associated kinase signaling within stroma, significantly decreased in vivo primary tumor growth, metastasis and improved response to standard-of-care therapy in pancreatic cancer. Automated analysis of collagen organization in pati...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Chin, Venessa T., Vennin, Claire, Timpson, Paul, Pajic, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644476/
https://ncbi.nlm.nih.gov/pubmed/29057302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1333973
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