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Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes. Remodeling of the pancreatic stroma occurs during PDAC development, which drives disease progressio...

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Detalles Bibliográficos
Publicado en:Small GTPases
Autores principales: Vennin, Claire, Rath, Nicola, Pajic, Marina, Olson, Michael F., Timpson, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959285/
https://ncbi.nlm.nih.gov/pubmed/28972449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1345712
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