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Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes. Remodeling of the pancreatic stroma occurs during PDAC development, which drives disease progressio...

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Publicat a:Small GTPases
Autors principals: Vennin, Claire, Rath, Nicola, Pajic, Marina, Olson, Michael F., Timpson, Paul
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959285/
https://ncbi.nlm.nih.gov/pubmed/28972449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1345712
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