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Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta
The PKC isozymes represent the most prominent family of signaling proteins mediating response to the ubiquitous second messenger diacylglycerol. Among them, PKCθ is critically involved in T-cell activation. Whereas all the other conventional and novel PKC isoforms have twin C1 domains with potent bi...
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| 出版年: | Biochim Biophys Acta Biomembr |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957261/ https://ncbi.nlm.nih.gov/pubmed/29317197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.01.007 |
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