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Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1

BACKGROUND: Resveratrol (1) is a naturally occurring polyphenol that has been implicated in neuroprotection. One of resveratrol’s several biological targets is Ca(2+)-sensitive protein kinase C alpha (PKCα). Resveratrol inhibits PKCα by binding to its activator-binding C1 domain. Munc13-1 is a C1 do...

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Bibliografische gegevens
Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Pany, Satyabrata, Ghosh, Anamitra, You, Youngki, Nguyen, Nga, Das, Joydip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623624/
https://ncbi.nlm.nih.gov/pubmed/28713022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.07.006
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