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Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1
BACKGROUND: Resveratrol (1) is a naturally occurring polyphenol that has been implicated in neuroprotection. One of resveratrol’s several biological targets is Ca(2+)-sensitive protein kinase C alpha (PKCα). Resveratrol inhibits PKCα by binding to its activator-binding C1 domain. Munc13-1 is a C1 do...
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| Publié dans: | Biochim Biophys Acta |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623624/ https://ncbi.nlm.nih.gov/pubmed/28713022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.07.006 |
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