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Munc13 Is a Molecular Target of Bryostatin 1

[Image: see text] Bryostatin 1 is a natural macrolide shown to improve neuronal connections and enhance memory in mice. Its mechanism of action is largely attributed to the modulation of novel and conventional protein kinase Cs (PKCs) by binding to their regulatory C1 domains. Munc13-1 is a C1 domai...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Blanco, Francisco A., Czikora, Agnes, Kedei, Noemi, You, Youngki, Mitchell, Gary A., Pany, Satyabrata, Ghosh, Anamitra, Blumberg, Peter M., Das, Joydip
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620733/
https://ncbi.nlm.nih.gov/pubmed/31243993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00427
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