Munc13 Is a Molecular Target of Bryostatin 1

[Image: see text] Bryostatin 1 is a natural macrolide shown to improve neuronal connections and enhance memory in mice. Its mechanism of action is largely attributed to the modulation of novel and conventional protein kinase Cs (PKCs) by binding to their regulatory C1 domains. Munc13-1 is a C1 domai...

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Bibliographic Details
Published in:	Biochemistry
Main Authors:	Blanco, Francisco A., Czikora, Agnes, Kedei, Noemi, You, Youngki, Mitchell, Gary A., Pany, Satyabrata, Ghosh, Anamitra, Blumberg, Peter M., Das, Joydip
Format:	Artigo
Language:	Inglês
Published:	American Chemical Society 2019
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6620733/ https://ncbi.nlm.nih.gov/pubmed/31243993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00427
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Munc13 Is a Molecular Target of Bryostatin 1

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