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Curcumin inhibits PKCα activity by binding to its C1 domain
Curcumin is a polyphenolic nutraceutical that acts on multiple biological targets, including protein kinase C (PKC). PKC is a family of serine-threonine kinases central to intracellular signal transduction. We have recently shown that curcumin selectively inhibits PKCα, but not PKCε in CHO-K1 cells...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657492/ https://ncbi.nlm.nih.gov/pubmed/27776404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00932 |
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