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Curcumin inhibits PKCα activity by binding to its C1 domain

Curcumin is a polyphenolic nutraceutical that acts on multiple biological targets, including protein kinase C (PKC). PKC is a family of serine-threonine kinases central to intracellular signal transduction. We have recently shown that curcumin selectively inhibits PKCα, but not PKCε in CHO-K1 cells...

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Podrobná bibliografie
Vydáno v:Biochemistry
Hlavní autoři: Pany, Satyabrata, You, Youngki, Das, Joydip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657492/
https://ncbi.nlm.nih.gov/pubmed/27776404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00932
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