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Regulatory T cells control PF4/heparin antibody production in mice
Heparin-induced thrombocytopenia (HIT) is a relatively common drug-induced immune disorder that can have life-threatening consequences for affected patients. Immune complexes consisting of heparin, platelet factor 4 (PF4) and PF4/heparin-reactive antibodies are central to the pathogenesis of HIT. Re...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944762/ https://ncbi.nlm.nih.gov/pubmed/31471526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900196 |
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