SARS-CoV-2 receptor binding domain-specific antibodies activate platelets with features resembling the pathogenic antibodies in heparin-induced thrombocytopenia

Severe COVID-19 is associated with unprecedented thromboembolic complications. We found that hospitalized COVID-19 patients develop immunoglobulin Gs (IgGs) that recognize a complex consisting of platelet factor 4 and heparin similar to those developed in heparin-induced thrombocytopenia and thrombo...

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Publicado no:Res Sq
Main Authors: Zhu, Wen, Zheng, Yongwei, Yu, Mei, Wei, Jianhui, Zhang, Yongguang, Topchyan, Paytsar, Nguyen, Christine, Janecke, Rae, Kreuziger, Lisa Baumann, White, Gilbert C., Hari, Parameswaran, Aster, Richard, Cui, Weiguo, Jobe, Shawn, Graham, Mary Beth, Wang, Demin, Wen, Renren
Formato: Artigo
Idioma:Inglês
Publicado em: American Journal Experts 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132233/
https://ncbi.nlm.nih.gov/pubmed/34013243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21203/rs.3.rs-462080/v1
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