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Regulatory T cells control PF4/heparin antibody production in mice

Heparin-induced thrombocytopenia (HIT) is a relatively common drug-induced immune disorder that can have life-threatening consequences for affected patients. Immune complexes consisting of heparin, platelet factor 4 (PF4) and PF4/heparin-reactive antibodies are central to the pathogenesis of HIT. Re...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Zheng, Yongwei, Zhu, Wen, Haribhai, Dipica, Williams, Calvin B., Aster, Richard H., Wen, Renren, Wang, Demin
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944762/
https://ncbi.nlm.nih.gov/pubmed/31471526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900196
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