Crystal structure of the M(5) muscarinic acetylcholine receptor

The human M(5) muscarinic acetylcholine receptor (mAChR) has recently emerged as an exciting therapeutic target for treating a range of disorders, including drug addiction. However, a lack of structural information for this receptor subtype has limited further drug development and validation. Here w...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Vuckovic, Ziva, Gentry, Patrick R., Berizzi, Alice E., Hirata, Kunio, Varghese, Swapna, Thompson, Geoff, van der Westhuizen, Emma T., Burger, Wessel A. C., Rahmani, Raphaël, Valant, Celine, Langmead, Christopher J., Lindsley, Craig W., Baell, Jonathan B., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926013/
https://ncbi.nlm.nih.gov/pubmed/31772027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914446116
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