Mutation S115T in IMP-Type Metallo-β-Lactamases Compensates for Decreased Expression Levels Caused by Mutation S119G

(1) Background: Metallo-β-lactamases (MBLs) have raised concerns due to their ability to inactivate carbapenems and newer generation cephalosporins and the absence of clinically available MBL inhibitors. Their genes are often transferred horizontally, and the number of MBL variants has grown exponen...

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Bibliografiska uppgifter
I publikationen:Biomolecules
Huvudupphovsmän: Zhang, Charles J., Faheem, Mohammad, Dang, Paulie, Morris, Monica N., Kumar, Pooja, Oelschlaeger, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920813/
https://ncbi.nlm.nih.gov/pubmed/31718049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110724
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