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Mutation S115T in IMP-Type Metallo-β-Lactamases Compensates for Decreased Expression Levels Caused by Mutation S119G

(1) Background: Metallo-β-lactamases (MBLs) have raised concerns due to their ability to inactivate carbapenems and newer generation cephalosporins and the absence of clinically available MBL inhibitors. Their genes are often transferred horizontally, and the number of MBL variants has grown exponen...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Zhang, Charles J., Faheem, Mohammad, Dang, Paulie, Morris, Monica N., Kumar, Pooja, Oelschlaeger, Peter
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920813/
https://ncbi.nlm.nih.gov/pubmed/31718049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110724
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