Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution

Antibiotic resistance in bacteria is ever changing and adapting, as once-novel β-lactam antibiotics are losing their efficacy, primarily due to the production of β-lactamases. Metallo-β-lactamases (MBLs) efficiently inactivate a broad range of β-lactam antibiotics, including carbapenems, and are oft...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: LaCuran, Alecander E., Pegg, Kevin M., Liu, Eleanor M., Bethel, Christopher R., Ai, Ni, Welsh, William J., Bonomo, Robert A., Oelschlaeger, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649200/
https://ncbi.nlm.nih.gov/pubmed/26369960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01651-15
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