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Biochemical Characterization of IMP-30, a Metallo-β-Lactamase with Enhanced Activity toward Ceftazidime

IMP-type enzymes constitute a clinically important family of metallo-β-lactamases that has grown dramatically in the past decade to its current 45 known members. Here, we report the biochemical characterization of IMP-30 in comparison to IMP-1, from which it deviates by a single E59K mutation. Kinet...

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Detalhes bibliográficos
Main Authors: Pegg, Kevin M., Liu, Eleanor M., LaCuran, Alecander E., Oelschlaeger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811441/
https://ncbi.nlm.nih.gov/pubmed/23836186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02341-12
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