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Mutation S115T in IMP-Type Metallo-β-Lactamases Compensates for Decreased Expression Levels Caused by Mutation S119G

(1) Background: Metallo-β-lactamases (MBLs) have raised concerns due to their ability to inactivate carbapenems and newer generation cephalosporins and the absence of clinically available MBL inhibitors. Their genes are often transferred horizontally, and the number of MBL variants has grown exponen...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Zhang, Charles J., Faheem, Mohammad, Dang, Paulie, Morris, Monica N., Kumar, Pooja, Oelschlaeger, Peter
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920813/
https://ncbi.nlm.nih.gov/pubmed/31718049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110724
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