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Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo
Lysosomal acidification is a key feature of healthy cells. Inability to maintain lysosomal acidic pH is associated with aging and neurodegenerative diseases. However, the mechanisms elicited by impaired lysosomal acidification remain poorly understood. We show here that inhibition of lysosomal acidi...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6917501/ https://ncbi.nlm.nih.gov/pubmed/31793879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51031 |
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