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Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis

Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we demonstrate that mitochondrial respiratory chai...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fernández-Mosquera, Lorena, Diogo, Cátia V., Yambire, King Faisal, Santos, Gabriela L., Luna Sánchez, Marta, Bénit, Paule, Rustin, Pierre, Lopez, Luis Carlos, Milosevic, Ira, Raimundo, Nuno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366864/
https://ncbi.nlm.nih.gov/pubmed/28345620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45076
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