Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis

Mitochondria are key organelles for cellular metabolism, and regulate several processes including cell death and macroautophagy/autophagy. Here, we show that mitochondrial respiratory chain (RC) deficiency deactivates AMP-activated protein kinase (AMPK, a key regulator of energy homeostasis) signali...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Fernandez-Mosquera, Lorena, Yambire, King Faisal, Couto, Renata, Pereyra, Leonardo, Pabis, Kamil, Ponsford, Amy H., Diogo, Cátia V., Stagi, Massimiliano, Milosevic, Ira, Raimundo, Nuno
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693470/
https://ncbi.nlm.nih.gov/pubmed/30917721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1586256
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