Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo

Lysosomal acidification is a key feature of healthy cells. Inability to maintain lysosomal acidic pH is associated with aging and neurodegenerative diseases. However, the mechanisms elicited by impaired lysosomal acidification remain poorly understood. We show here that inhibition of lysosomal acidi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Yambire, King Faisal, Rostosky, Christine, Watanabe, Takashi, Pacheu-Grau, David, Torres-Odio, Sylvia, Sanchez-Guerrero, Angela, Senderovich, Ola, Meyron-Holtz, Esther G, Milosevic, Ira, Frahm, Jens, West, A Phillip, Raimundo, Nuno
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917501/
https://ncbi.nlm.nih.gov/pubmed/31793879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51031
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak