Llwytho...
Binding of N(8)-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation
Eukaryotic histone deacetylase 10 (HDAC10) is a Zn(2+)-dependent hydrolase that exhibits catalytic specificity for the hydrolysis of the polyamine N(8)-acetylspermidine. The recently determined crystal structure of HDAC10 from Danio rerio (zebrafish) reveals a narrow active site cleft and a negative...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Biochemistry |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6904438/ https://ncbi.nlm.nih.gov/pubmed/31746596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00906 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|