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Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of biological macromolecules. Intracellular polyamine metabolism is regulated by reversible acetylation and dysregulated polyamine metabolism is associated with neoplastic diseases su...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hai, Yang, Shinsky, Stephen A., Porter, Nicholas J., Christianson, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454378/
https://ncbi.nlm.nih.gov/pubmed/28516954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15368
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