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A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion

The Hippo pathway is an emerging signaling pathway that plays important roles in organ size control, tissue homeostasis, tumorigenesis, metastasis, drug resistance, and immune response. Although many regulators of the Hippo pathway have been reported, the extracellular stimuli and kinase regulators...

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Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Nouri,, Kazem, Azad,, Taha, Lightbody, Elizabeth, Khanal, Prem, Nicol, Christopher J., Yang, Xiaolong
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902680/
https://ncbi.nlm.nih.gov/pubmed/31431076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901343R
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