A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion

The Hippo pathway is an emerging signaling pathway that plays important roles in organ size control, tissue homeostasis, tumorigenesis, metastasis, drug resistance, and immune response. Although many regulators of the Hippo pathway have been reported, the extracellular stimuli and kinase regulators...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Nouri,, Kazem, Azad,, Taha, Lightbody, Elizabeth, Khanal, Prem, Nicol, Christopher J., Yang, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902680/
https://ncbi.nlm.nih.gov/pubmed/31431076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901343R
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