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Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor

The Hippo signaling pathway is a conserved regulator of organ size and has important roles in the development and cancer biology. Due to technical challenges, it remains difficult to assess the activity of this signaling pathway and interpret it within a biological context. The existing literature o...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Azad, Taha, Nouri, Kazem, Janse van Rensburg, Helena J., Hao, Yawei, Yang, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235178/
https://ncbi.nlm.nih.gov/pubmed/30272653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58416
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