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Utilizing split-NanoLuc luciferase fragments as luminescent probes for protein solubility in living cells

Protein misfolding and aggregation is now recognized as a hallmark of numerous human diseases. Standard bioanalytical techniques for monitoring protein aggregation generally rely on small molecules that provide an optical readout of fibril formation. While these methods have been useful for mechanis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Methods Enzymol
Prif Awduron: Nelson, Travis J., Zhao, Jia, Stains, Cliff I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567984/
https://ncbi.nlm.nih.gov/pubmed/31155065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.003
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