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Utilizing split-NanoLuc luciferase fragments as luminescent probes for protein solubility in living cells
Protein misfolding and aggregation is now recognized as a hallmark of numerous human diseases. Standard bioanalytical techniques for monitoring protein aggregation generally rely on small molecules that provide an optical readout of fibril formation. While these methods have been useful for mechanis...
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| 發表在: | Methods Enzymol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6567984/ https://ncbi.nlm.nih.gov/pubmed/31155065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.003 |
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